Comparative analysis of Shigella and Campylobacter transmission in paired longitudinal household cohort studies in urban Bangladesh and rural Tanzania
· 2026-09-04 · 原文
DOI：10.64898/2026.09.01.26361896v1?rss=1预印本：medRxiv开放获取：绿色OA
Background: Transmission pathways of enteric pathogens have been broadly characterized; however, the degree to which different pathogens exploit different transmission routes and how these patterns vary across age remain poorly understood. We quantified the relative contribution of within-household (infection sources internal to the household) and community-to-household (infection sources external to the household) transmission for Shigella and Campylobacter. Methods: We conducted paired longitudinal cohort studies in urban Bangladesh and rural Tanzania, each enrolling 100 households with a child under the age of one year. Stool samples were collected from participants' households monthly and during diarrheal episodes for one year. We estimated daily infection trajectories for each partici
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1. 人话版
Background: Transmission pathways of enteric pathogens have been broadly characterized; however, the degree to which different pathogens exploit different transmission routes and how these patterns vary across age remain poorly understood.
We quantified the relative contribution of within-household (infection sources internal to the household) and community-to-household (infection sources external to the household) transmission for Shigella and Campylobacter.
2. 领域脉络
来源板块：板块一 · 研究前沿。
3. 机制拆解
Stool samples were collected from participants' households monthly and during diarrheal episodes for one year.
We estimated daily infection trajectories for each partici
4. 证据与数字
Methods: We conducted paired longitudinal cohort studies in urban Bangladesh and rural Tanzania, each enrolling 100 households with a child under the age of one year.
5. 反例与边界
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