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Coronary revascularisation in people with multiple long-term conditions: a systematic review and meta-analysis

· 2026-09-08 · 原文

DOI:10.64898/2026.09.04.26362027v1?rss=1

Introduction People presenting for multivessel coronary revascularisation commonly have multiple long-term conditions that influence prognosis. The aim of this study was to review the evidence for revascularisation choices in these groups. Methods Randomised trials of Coronary Artery Bypass Grafting (CABG) versus Percutaneous Coronary Intervention (PCI) reporting outcomes by pre-specified comorbidities were included. Treatment effects were estimated using inverse variance random effects models and presented as Risk Ratios (95% Confidence Intervals). The certainty of evidence for outcomes was assessed using Grading of Recommendations Assessment, Development and Evaluation (GRADE). Results 19 studies from nine RCTs with 10,594 participants were included. Reported baseline comorbidities inclu

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1. 人话版

Introduction People presenting for multivessel coronary revascularisation commonly have multiple long-term conditions that influence prognosis.

The aim of this study was to review the evidence for revascularisation choices in these groups.

2. 领域脉络

Methods Randomised trials of Coronary Artery Bypass Grafting (CABG) versus Percutaneous Coronary Intervention (PCI) reporting outcomes by pre-specified comorbidities were included.

3. 机制拆解

The certainty of evidence for outcomes was assessed using Grading of Recommendations Assessment, Development and Evaluation (GRADE).

4. 证据与数字

Treatment effects were estimated using inverse variance random effects models and presented as Risk Ratios (95% Confidence Intervals).

Results 19 studies from nine RCTs with 10,594 participants were included.

5. 反例与边界

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6. 跨领域连接与意外收获

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7. 可复用方法

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8. 术语表

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