Mesoscale functional architecture in medial posterior parietal cortex
· 2026-09-02 · 原文
The posterior parietal cortex (PPC) in mice has various functions, including multisensory integration, vision-guided behaviors, working memory, and posture control. However, an integrated understanding of these functions and their cortical localizations in and around the PPC and higher visual areas (HVAs) has not been completely elucidated. Here, we simultaneously imaged the activity of thousands of neurons within a 3 × 3 mm 2 field of view, including eight cortical areas around the PPC, during behavior with a two-photon mesoscope. Mice performed both a vision-guided task and a choice history-dependent task, and the imaging results revealed distinct, localized, and behavior-related functions of two medial PPC areas. Neurons in the anteromedial (AM) HVA responded to both vision and choice i
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1. 人话版
The posterior parietal cortex (PPC) in mice has various functions, including multisensory integration, vision-guided behaviors, working memory, and posture control.
However, an integrated understanding of these functions and their cortical localizations in and around the PPC and higher visual areas (HVAs) has not been completely elucidated.
2. 领域脉络
来源板块：板块二 · 顶级期刊。
3. 机制拆解
Mice performed both a vision-guided task and a choice history-dependent task, and the imaging results revealed distinct, localized, and behavior-related functions of two medial PPC areas.
Neurons in the anteromedial (AM) HVA responded to both vision and choice i
4. 证据与数字
Here, we simultaneously imaged the activity of thousands of neurons within a 3 × 3 mm 2 field of view, including eight cortical areas around the PPC, during behavior with a two-photon mesoscope.
5. 反例与边界
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6. 跨领域连接与意外收获
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7. 可复用方法
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8. 术语表
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