Patient and Public Involvement in designing a clinical trial for the surgical management of persistent Post-Infectious Olfactory Dysfunction
· 2026-09-10 · 原文
DOI：10.64898/2026.09.08.26362544v1?rss=1
Introduction: Persistent post-infectious olfactory dysfunction (PIOD) has limited effective treatments. In developing a randomized controlled trial (RCT) to evaluate a novel surgical intervention for persistent PIOD, embedding Patient and Public Involvement (PPI), a core NIHR requirement in research, was essential. Objectives: To outline the PPI programme for our proposed RCT, in line with UK Standards for Public Involvement. The objective of the PPI programme was to design a patient-centred, inclusive, and ethically sound trial. Methods: The PPI programme included an online survey, online discussion forums, and focus groups. Results: 63 survey responses, 2 online discussion forums, and 2 focus groups provided PPI input on control arm acceptability, participant recruitment and retention st
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1. 人话版
Introduction: Persistent post-infectious olfactory dysfunction (PIOD) has limited effective treatments.
In developing a randomized controlled trial (RCT) to evaluate a novel surgical intervention for persistent PIOD, embedding Patient and Public Involvement (PPI), a core NIHR requirement in research, was essential.
2. 领域脉络
Objectives: To outline the PPI programme for our proposed RCT, in line with UK Standards for Public Involvement.
3. 机制拆解
The objective of the PPI programme was to design a patient-centred, inclusive, and ethically sound trial.
Methods: The PPI programme included an online survey, online discussion forums, and focus groups.
4. 证据与数字
Results: 63 survey responses, 2 online discussion forums, and 2 focus groups provided PPI input on control arm acceptability, participant recruitment and retention st
5. 反例与边界
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6. 跨领域连接与意外收获
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7. 可复用方法
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8. 术语表
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