Does a new randomized trial change the evidence? A pilot audit of evidence deltas in colorectal surgery
· 2026-09-09 · 原文
DOI：10.64898/2026.09.04.26362222v1?rss=1
Background. Research output is counted in publications, although publications differ in how much uncertainty they resolve. An evidence delta is the change between the evidence state immediately before an index trial's results are published and the evidence state after. Whether such a comparison can be reconstructed from the published record is unknown. Methods. Six colorectal-surgery evidence lineages were chosen by the first author before any outcome data were seen, each defined by one binary patient-relevant outcome. Randomized trials of any year were sought in PubMed and PubMed Central with multiple keyword and acronym strategies. One verbatim strategy per lineage was written afterwards, re-run and archived; the records it returned that had not already been assessed were screened on tit
讲义
讲义·推断 依据「原文」自动生成的结构化摘要（推断），非原文表述；以原文为准。
1. 人话版
Research output is counted in publications, although publications differ in how much uncertainty they resolve.
An evidence delta is the change between the evidence state immediately before an index trial's results are published and the evidence state after.
2. 领域脉络
Whether such a comparison can be reconstructed from the published record is unknown.
3. 机制拆解
Six colorectal-surgery evidence lineages were chosen by the first author before any outcome data were seen, each defined by one binary patient-relevant outcome.
Randomized trials of any year were sought in PubMed and PubMed Central with multiple keyword and acronym strategies.
4. 证据与数字
摘要未给出量化结果——留意原文的实验与数据。
5. 反例与边界
摘要未声明局限与反例——这是需要警惕的信号，精读时先问边界。
6. 跨领域连接与意外收获
思考本文机制能否迁移到你正在跟进的问题。
7. 可复用方法
把本文机制与你手头项目对照，找一个两周内能验证的最小实验。
8. 术语表
精读时把不熟的术语记入此处，作为下次回忆的锚点。