BrachyAtlas: Patient-Specific Virtual Planning for Intracavitary Cesium-131 Brachytherapy with Tile Placement, Dose Calculation, and Modeled Neuroanatomical Exposure
· 2026-09-09 · 原文
DOI：10.64898/2026.09.06.26362396v1?rss=1预印本：medRxiv
Background: Brachytherapy delivers localized radiation from sources placed within or adjacent to tissue at risk. In brain tumor surgery, intracavitary implantation can begin at resection and concentrate dose along the cavity wall, where many recurrences arise. Current preoperative GammaTile tools estimate tile requirements but not patient-specific placement, resulting dose, or adjacent anatomy. We developed an integrated software framework for patient-specific virtual GammaTile planning. Methods: The framework incorporates AI-assisted tumor and cavity segmentation with user approval, converts accepted masks into patient-derived surfaces, supports virtual tile placement, calculates lifetime Cs-131 dose using TG-43, maps dose distributions to HCP-MMP cortical parcels and normative HCP-1065 w
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1. 人话版
Background: Brachytherapy delivers localized radiation from sources placed within or adjacent to tissue at risk.
In brain tumor surgery, intracavitary implantation can begin at resection and concentrate dose along the cavity wall, where many recurrences arise.
2. 领域脉络
来源板块：板块一 · 研究前沿。
3. 机制拆解
We developed an integrated software framework for patient-specific virtual GammaTile planning.
4. 证据与数字
Methods: The framework incorporates AI-assisted tumor and cavity segmentation with user approval, converts accepted masks into patient-derived surfaces, supports virtual tile placement, calculates lifetime Cs-131 dose using TG-43, maps dose distributions to HCP-MMP cortical parcels and normative HCP-1065 w
5. 反例与边界
Current preoperative GammaTile tools estimate tile requirements but not patient-specific placement, resulting dose, or adjacent anatomy.
6. 跨领域连接与意外收获
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7. 可复用方法
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8. 术语表
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