Concordance Between a Temple-Worn Optical Wearable and Transcranial Doppler During Exercise and Postural Transitions in Healthy Adults
· 2026-09-04 · 原文
DOI：10.64898/2026.09.02.26362022v1?rss=1预印本：medRxiv
Cerebral hemodynamics are difficult to monitor continuously outside the laboratory. Optical head-worn wearables have been proposed for tracking cerebral blood-flow signals, but they require comparison with an established cerebrovascular reference before they can be interpreted. We evaluated a temple-worn optical wearable, Temple, that outputs a proprietary, dimensionless Brain Flow index, intended as a proxy for relative changes in cerebral hemodynamics, against transcranial Doppler (TCD) ultrasound, which measures blood-flow velocity in the middle cerebral artery (MCAv). Twenty-three healthy adults completed two physiological challenges that elicit distinct and acute cerebral hemodynamic responses: a cycle-ergometer exercise protocol and a stand-to-supine postural transition protocol. Twe
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1. 人话版
Cerebral hemodynamics are difficult to monitor continuously outside the laboratory.
Optical head-worn wearables have been proposed for tracking cerebral blood-flow signals, but they require comparison with an established cerebrovascular reference before they can be interpreted.
2. 领域脉络
We evaluated a temple-worn optical wearable, Temple, that outputs a proprietary, dimensionless Brain Flow index, intended as a proxy for relative changes in cerebral hemodynamics, against transcranial Doppler (TCD) ultrasound, which measures blood-flow velocity in the middle cerebral artery (MCAv).
3. 机制拆解
Twenty-three healthy adults completed two physiological challenges that elicit distinct and acute cerebral hemodynamic responses: a cycle-ergometer exercise protocol and a stand-to-supine postural transition protocol.
4. 证据与数字
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5. 反例与边界
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6. 跨领域连接与意外收获
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7. 可复用方法
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8. 术语表
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