In Vivo K-edge Imaging on a Clinical Dual-source PCCT: Feasibility of Gadolinium Applications in a Porcine Model
· 2026-09-09 · 原文
DOI：10.64898/2026.09.07.26362472v1?rss=1预印本：medRxiv开放获取：绿色OA
Objectives: To evaluate the feasibility of in vivo gadolinium K-edge imaging on a clinical dual-source photon-counting CT (PCCT) system in a porcine model and to assess its performance for dynamic contrast-enhanced imaging, functional biliary imaging, and dual-contrast (bi-phasic) imaging. Materials and Methods: A single healthy Yorkshire-Landrace pig was imaged on a clinical dual-source PCCT system (140 kVp; energy thresholds 20/55/72/90 keV; CTDIvol 12 mGy). Gadolinium K edge material-specific maps were generated with a calibration-based least-squares material decomposition. Three imaging protocols were evaluated for feasibility: (A) contrast dose testing for dynamic imaging with a hepatobiliary-clearing gadolinium contrast agent (0.2 and 0.8 mL/kg); (B) functional biliary imaging with d
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1. 人话版
Objectives: To evaluate the feasibility of in vivo gadolinium K-edge imaging on a clinical dual-source photon-counting CT (PCCT) system in a porcine model and to assess its performance for dynamic contrast-enhanced imaging, functional biliary imaging, and dual-contrast (bi-phasic) imaging.
Materials and Methods: A single healthy Yorkshire-Landrace pig was imaged on a clinical dual-source PCCT system (140 kVp; energy thresholds 20/55/72/90 keV; CTDIvol 12 mGy).
2. 领域脉络
Gadolinium K edge material-specific maps were generated with a calibration-based least-squares material decomposition.
3. 机制拆解
摘要未展开方法细节——精读时重点看方法/模型部分。
4. 证据与数字
Three imaging protocols were evaluated for feasibility: (A) contrast dose testing for dynamic imaging with a hepatobiliary-clearing gadolinium contrast agent (0.2 and 0.8 mL/kg); (B) functional biliary imaging with d
5. 反例与边界
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6. 跨领域连接与意外收获
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7. 可复用方法
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8. 术语表
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