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Meaning of clinical calculator results: a cross-sectional analysis of the MDCalc catalogue

· 2026-09-10 · 原文

DOI:10.64898/2026.09.08.26362556v1?rss=1

Objectives To quantify complementary meanings of binary clinical calculator results: information beyond the observed outcome frequency, post-result risk, information direction, and precision. Design Catalogue-based cross-sectional analysis of published aggregate performance data, with a reproducible row-level audit. Setting The 847-calculator MDCalc catalogue and a fixed collection of publicly available reports assembled without a systematic literature search. Participants Evaluations comparing a binary calculator result with a binary clinical outcome using a complete or reconstructable 2 x 2 table. Main outcome measures Percentage reduction in uncertainty and corresponding information gain in bits; risk after positive and negative classifications; the proportion of information from each c

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1. 人话版

Objectives To quantify complementary meanings of binary clinical calculator results: information beyond the observed outcome frequency, post-result risk, information direction, and precision.

Design Catalogue-based cross-sectional analysis of published aggregate performance data, with a reproducible row-level audit.

2. 领域脉络

来源板块:板块一 · 研究前沿。

3. 机制拆解

Main outcome measures Percentage reduction in uncertainty and corresponding information gain in bits; risk after positive and negative classifications; the proportion of information from each c

4. 证据与数字

Setting The 847-calculator MDCalc catalogue and a fixed collection of publicly available reports assembled without a systematic literature search.

Participants Evaluations comparing a binary calculator result with a binary clinical outcome using a complete or reconstructable 2 x 2 table.

5. 反例与边界

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